High-Throughput Analysis of NF-κB Dynamics in Single Cells Reveals Basal Nuclear Localization of NF-κB and Spontaneous Activation of Oscillations

NF-κB is a transcription factor that upon activation undergoes cycles of cytoplasmic-to-nuclear and nuclear-to-cytoplasmic transport, giving rise to so called “oscillations”. In turn, oscillations tune the transcriptional output. Since a detailed understanding of oscillations requires a systems biol...

Descripción completa

Detalles Bibliográficos
Autores principales: Zambrano, Samuel, Bianchi, Marco E., Agresti, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942427/
https://www.ncbi.nlm.nih.gov/pubmed/24595030
http://dx.doi.org/10.1371/journal.pone.0090104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942427/
https://www.ncbi.nlm.nih.gov/pubmed/24595030
http://dx.doi.org/10.1371/journal.pone.0090104

Ejemplares similares