Peripheral Sensitization Increases Opioid Receptor Expression and Activation by Crotalphine in Rats

Inflammation enhances the peripheral analgesic efficacy of opioid drugs, but the mechanisms involved in this phenomenon have not been fully elucidated. Crotalphine (CRP), a peptide that was first isolated from South American rattlesnake C.d. terrificus venom, induces a potent and long-lasting anti-n...

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Detalles Bibliográficos
Autores principales: Zambelli, Vanessa Olzon, Fernandes, Ana Carolina de Oliveira, Gutierrez, Vanessa Pacciari, Ferreira, Julio Cesar Batista, Parada, Carlos Amilcar, Mochly-Rosen, Daria, Cury, Yara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942445/
https://www.ncbi.nlm.nih.gov/pubmed/24594607
http://dx.doi.org/10.1371/journal.pone.0090576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942445/
https://www.ncbi.nlm.nih.gov/pubmed/24594607
http://dx.doi.org/10.1371/journal.pone.0090576

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