Pitx2c Is Reactivated in the Failing Myocardium and Stimulates Myf5 Expression in Cultured Cardiomyocytes

BACKGROUND: Pitx2 (paired-like homeodomain 2 transcription factor) is crucial for heart development, but its role in heart failure (HF) remains uncertain. The present study lays the groundwork implicating Pitx2 signalling in different modalities of HF. METHODOLOGY/PRINCIPAL FINDINGS: A variety of mo...

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Detalles Bibliográficos
Autores principales: Torrado, Mario, Franco, Diego, Hernández-Torres, Francisco, Crespo-Leiro, María G., Iglesias-Gil, Carmen, Castro-Beiras, Alfonso, Mikhailov, Alexander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942452/
https://www.ncbi.nlm.nih.gov/pubmed/24595098
http://dx.doi.org/10.1371/journal.pone.0090561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942452/
https://www.ncbi.nlm.nih.gov/pubmed/24595098
http://dx.doi.org/10.1371/journal.pone.0090561

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