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High Fat Diet Rapidly Suppresses B Lymphopoiesis by Disrupting the Supportive Capacity of the Bone Marrow Niche

The bone marrow (BM) niche is the primary site of hematopoiesis, and cues from this microenvironment are critical to maintain hematopoiesis. Obesity increases lifetime susceptibility to a host of chronic diseases, and has been linked to defective leukogenesis. The pressures obesity exerts on hematop...

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Detalles Bibliográficos
Autores principales: Adler, Benjamin J., Green, Danielle E., Pagnotti, Gabriel M., Chan, M. Ete, Rubin, Clinton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942453/
https://www.ncbi.nlm.nih.gov/pubmed/24595332
http://dx.doi.org/10.1371/journal.pone.0090639