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High Fat Diet Rapidly Suppresses B Lymphopoiesis by Disrupting the Supportive Capacity of the Bone Marrow Niche
The bone marrow (BM) niche is the primary site of hematopoiesis, and cues from this microenvironment are critical to maintain hematopoiesis. Obesity increases lifetime susceptibility to a host of chronic diseases, and has been linked to defective leukogenesis. The pressures obesity exerts on hematop...
Autores principales: | Adler, Benjamin J., Green, Danielle E., Pagnotti, Gabriel M., Chan, M. Ete, Rubin, Clinton T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942453/ https://www.ncbi.nlm.nih.gov/pubmed/24595332 http://dx.doi.org/10.1371/journal.pone.0090639 |
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