Evaluation of Fentanyl Disposition and Effects in Newborn Piglets as an Experimental Model for Human Neonates

BACKGROUND: Fentanyl is widely used off-label in NICU. Our aim was to investigate its cerebral, cardiovascular and pulmonary effects as well as pharmacokinetics in an experimental model for neonates. METHODS: Fentanyl (5 µg/kg bolus immediately followed by a 90 minute infusion of 3 µg/kg/h) was admi...

Descripción completa

Detalles Bibliográficos
Autores principales: Rey-Santano, Carmen, Mielgo, Victoria, Valls-i-Soler, Adolfo, Encinas, Esther, Lukas, John C., Vozmediano, Valvanera, Suárez, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942469/
https://www.ncbi.nlm.nih.gov/pubmed/24595018
http://dx.doi.org/10.1371/journal.pone.0090728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942469/
https://www.ncbi.nlm.nih.gov/pubmed/24595018
http://dx.doi.org/10.1371/journal.pone.0090728

Ejemplares similares