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Ursodeoxycholic Acid Ameliorates Pain Severity and Cartilage Degeneration in Monosodium Iodoacetate-Induced Osteoarthritis in Rats

Osteoarthritis (OA) is a degenerative joint disease characterized by a progressive loss of cartilage. And, increased oxidative stress plays a relevant role in the pathogenesis of OA. Ursodeoxycholic acid (UDCA) is a used drug for liver diseases known for its free radical-scavenging property. The obj...

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Detalles Bibliográficos
Autores principales: Moon, Su-Jin, Jeong, Jeong-Hee, Jhun, Joo Yeon, Yang, Eun Ji, Min, Jun-Ki, Choi, Jong Young, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942507/
https://www.ncbi.nlm.nih.gov/pubmed/24605080
http://dx.doi.org/10.4110/in.2014.14.1.45