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Calcium dependent regulation of Rab activation and vesicle fusion by an intracellular P2X ion channel

Rab GTPases play key roles in the delivery, docking and fusion of intracellular vesicles. However, the mechanism by which spatial and temporal regulation of Rab GTPase activity is controlled is poorly understood. Here we describe a mechanism by which localized calcium release through a vesicular ion...

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Detalles Bibliográficos
Autores principales: Parkinson, Katie, Baines, Abigail E., Keller, Thomas, Gruenheit, Nicole, Bragg, Laricia, North, R. Alan, Thompson, Christopher R.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942655/
https://www.ncbi.nlm.nih.gov/pubmed/24335649
http://dx.doi.org/10.1038/ncb2887