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Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens

Staphylococcus aureus and group A Streptococcus secrete a collection of toxins called superantigens (SAgs), so-called because they stimulate a large fraction of an individual’s T cells. One consequence of this hyperactivity is massive cytokine release leading to severe tissue inflammation and, in so...

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Detalles Bibliográficos
Autores principales: Sharma, Preeti, Wang, Ningyan, Kranz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942751/
https://www.ncbi.nlm.nih.gov/pubmed/24476714
http://dx.doi.org/10.3390/toxins6020556