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β-lapachone ameliorates murine cisplatin nephrotoxicty – NAD+, NQO1, and SIRT1 at the crossroads of metabolism, injury, and inflammation
The clinical utility of cisplatin is limited by nephrotoxicity. So et al report that β-lapachone prevents this nephrotoxicity but not cisplatin’s cytotoxicity for cancers. In addition to its potential clinical importance, the beneficial effect of β-lapachone on cisplatin AKI may illustrate fundament...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942788/ https://www.ncbi.nlm.nih.gov/pubmed/24583980 http://dx.doi.org/10.1038/ki.2013.419 |