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Brucella dissociation is essential for macrophage egress and bacterial dissemination

It has long been observed that smooth Brucella can dissociate into rough mutants that are cytotoxic to macrophages. However, the in vivo biological significance and/or mechanistic details of Brucella dissociation and cytotoxicity remain incomplete. In the current report, a plaque assay was developed...

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Detalles Bibliográficos
Autores principales: Pei, Jianwu, Kahl-McDonagh, Melissa, Ficht, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942807/
https://www.ncbi.nlm.nih.gov/pubmed/24634889
http://dx.doi.org/10.3389/fcimb.2014.00023