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Dermal Cell Damage Induced by Topical Application of Non-Steroidal Anti-Inflammatory Drugs is Suppressed by Trehalose Co-Lyophilization in Ex Vivo Analysis

Topical administration of non-steroidal anti-inflammatory drugs (NSAIDs) is generally considered safer than oral administration, although the former can occasionally induce cutaneous irritation. We hypothesized that the cutaneous irritation by topical NSAIDs might be suppressed by trehalose, which h...

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Detalles Bibliográficos
Autores principales: KAYASUGA-KARIYA, Yuko, IWANAGA, Shintaroh, FUJISAWA, Ayano, LIN, Lee-Shuan, SUZUKI, Shigeki, CHUNG, Ung-il, SASAKI, Nobuo, SHIMOHATA, Nobuyuki, MOCHIZUKI, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942957/
https://www.ncbi.nlm.nih.gov/pubmed/23884023
http://dx.doi.org/10.1292/jvms.12-0502