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Dermal Cell Damage Induced by Topical Application of Non-Steroidal Anti-Inflammatory Drugs is Suppressed by Trehalose Co-Lyophilization in Ex Vivo Analysis
Topical administration of non-steroidal anti-inflammatory drugs (NSAIDs) is generally considered safer than oral administration, although the former can occasionally induce cutaneous irritation. We hypothesized that the cutaneous irritation by topical NSAIDs might be suppressed by trehalose, which h...
Autores principales: | KAYASUGA-KARIYA, Yuko, IWANAGA, Shintaroh, FUJISAWA, Ayano, LIN, Lee-Shuan, SUZUKI, Shigeki, CHUNG, Ung-il, SASAKI, Nobuo, SHIMOHATA, Nobuyuki, MOCHIZUKI, Manabu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942957/ https://www.ncbi.nlm.nih.gov/pubmed/23884023 http://dx.doi.org/10.1292/jvms.12-0502 |
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