Role of Insulin Resistance in the Pathogenesis and Development of Type 2 Diabetes in WBN/Kob-Lepr(fa) Rats

WBN/Kob-Lepr(fa) (fa/fa) rats have been identified as a new animal model of type 2 diabetes (T2DM), as they are characterized by impaired pancreatic insulin secretion and severe insulin resistance. Our previous study demonstrated impaired insulin secretion and its involvement in hyperglycemia in fa/...

Descripción completa

Detalles Bibliográficos
Autores principales: OKUNO, Akira, KAJI, Noriyuki, TAKAHASHI, Atsushi, NAGAKUBO, Dai, OHNO-ICHIKI, Kanako, SHIRAI, Mitsuyuki, ASAI, Fumitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942958/
https://www.ncbi.nlm.nih.gov/pubmed/23892462
http://dx.doi.org/10.1292/jvms.13-0230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942958/
https://www.ncbi.nlm.nih.gov/pubmed/23892462
http://dx.doi.org/10.1292/jvms.13-0230

Ejemplares similares