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Role of Insulin Resistance in the Pathogenesis and Development of Type 2 Diabetes in WBN/Kob-Lepr(fa) Rats

WBN/Kob-Lepr(fa) (fa/fa) rats have been identified as a new animal model of type 2 diabetes (T2DM), as they are characterized by impaired pancreatic insulin secretion and severe insulin resistance. Our previous study demonstrated impaired insulin secretion and its involvement in hyperglycemia in fa/...

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Detalles Bibliográficos
Autores principales:	OKUNO, Akira, KAJI, Noriyuki, TAKAHASHI, Atsushi, NAGAKUBO, Dai, OHNO-ICHIKI, Kanako, SHIRAI, Mitsuyuki, ASAI, Fumitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942958/ https://www.ncbi.nlm.nih.gov/pubmed/23892462 http://dx.doi.org/10.1292/jvms.13-0230

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