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Dioxin Sensitivity-Related Two Critical Amino Acids of Arylhydrocarbon Receptor May Not Correlate with the Taxonomy or Phylogeny in Avian Species

There are two arylhydrocarbon receptor (AhR) isoforms in birds, AhR1 and AhR2. The varying sensitivity of AhR is reported to be related to two critical amino acids at positions 325 and 381 in the AhR1 ligand-binding domain. In this study, seven avian species whose in vivo dioxin sensitivity was know...

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Detalles Bibliográficos
Autores principales: FUJISAWA, Nozomi, KAWAI, Yusuke K., NAKAYAMA, Shouta M. M., IKENAKA, Yoshinori, YAMAMOTO, Hideaki, ISHIZUKA, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942959/
https://www.ncbi.nlm.nih.gov/pubmed/23912877
http://dx.doi.org/10.1292/jvms.13-0179