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Network analysis of metabolic enzyme evolution in Escherichia coli
BACKGROUND: The two most common models for the evolution of metabolism are the patchwork evolution model, where enzymes are thought to diverge from broad to narrow substrate specificity, and the retrograde evolution model, according to which enzymes evolve in response to substrate depletion. Analysi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC394313/ https://www.ncbi.nlm.nih.gov/pubmed/15113413 http://dx.doi.org/10.1186/1471-2105-5-15 |