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Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-ones via microwave-activated inverse electron-demand Diels–Alder reactions

Substituted 3,4-dihydro-1,8-naphthyridin-2(1H)-ones have been synthesized with the inverse electron-demand Diels–Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain. Alkynes were first subjected to the Sonogashira cross-coupling reaction with aryl halides...

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Detalles Bibliográficos
Autores principales: Fadel, Salah, Hajbi, Youssef, Khouili, Mostafa, Lazar, Said, Suzenet, Franck, Guillaumet, Gérald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943289/
https://www.ncbi.nlm.nih.gov/pubmed/24605148
http://dx.doi.org/10.3762/bjoc.10.24