Transferrin-Conjugated SNALPs Encapsulating 2′-O-Methylated miR-34a for the Treatment of Multiple Myeloma

Stable nucleic acid lipid vesicles (SNALPs) encapsulating miR-34a to treat multiple myeloma (MM) were developed. Wild type or completely 2′-O-methylated (OMet) MiR-34a was used in this study. Moreover, SNALPs were conjugated with transferrin (Tf) in order to target MM cells overexpressing transferri...

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Detalles Bibliográficos
Autores principales: Scognamiglio, Immacolata, Di Martino, Maria Teresa, Campani, Virginia, Virgilio, Antonella, Galeone, Aldo, Gullà, Annamaria, Gallo Cantafio, Maria Eugenia, Misso, Gabriella, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Caraglia, Michele, De Rosa, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943297/
https://www.ncbi.nlm.nih.gov/pubmed/24683542
http://dx.doi.org/10.1155/2014/217365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943297/
https://www.ncbi.nlm.nih.gov/pubmed/24683542
http://dx.doi.org/10.1155/2014/217365

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