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Can mutation and selection explain virulence in human P. falciparum infections?
BACKGROUND: Parasites incur periodic mutations which must ultimately be eliminated to maintain their genetic integrity. METHODS: It is hypothesised that these mutations are eliminated not by the conventional mechanisms of competition between parasites in different hosts but primarily by competition...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC394339/ https://www.ncbi.nlm.nih.gov/pubmed/14992697 http://dx.doi.org/10.1186/1475-2875-3-2 |