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Can mutation and selection explain virulence in human P. falciparum infections?

BACKGROUND: Parasites incur periodic mutations which must ultimately be eliminated to maintain their genetic integrity. METHODS: It is hypothesised that these mutations are eliminated not by the conventional mechanisms of competition between parasites in different hosts but primarily by competition...

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Detalles Bibliográficos
Autores principales: Hastings, Ian M, Paget-McNicol, S, Saul, A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC394339/
https://www.ncbi.nlm.nih.gov/pubmed/14992697
http://dx.doi.org/10.1186/1475-2875-3-2