Rosiglitazone Increases Cerebral Klotho Expression to Reverse Baroreflex in Type 1-Like Diabetic Rats

Reduced baroreflex sensitivity (BRS) is widely observed in diabetic human and animals. Rosiglitazone is one of the clinically used thiazolidinediones (TZD) known as PPARγ agonist. Additionally, the klotho protein produced from choroid plexus in the central nervous system is regulated by PPARγ. In an...

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Detalles Bibliográficos
Autores principales: Chen, Li-Jen, Cheng, Meng-Fu, Ku, Po-Ming, Lin, Jia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943406/
https://www.ncbi.nlm.nih.gov/pubmed/24683546
http://dx.doi.org/10.1155/2014/309151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943406/
https://www.ncbi.nlm.nih.gov/pubmed/24683546
http://dx.doi.org/10.1155/2014/309151

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