Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNA

BACKGROUND: Due to their modular repeat structure, Pumilio/fem-3 mRNA binding factor (PUF) proteins are promising candidates for designer RNA-binding protein (RBP) engineering. To further facilitate the application of the PUF domain for the sequence-specific RBP engineering, a rapid cloning approach...

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Detalles Bibliográficos
Autores principales: Abil, Zhanar, Denard, Carl A, Zhao, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943411/
https://www.ncbi.nlm.nih.gov/pubmed/24581042
http://dx.doi.org/10.1186/1754-1611-8-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943411/
https://www.ncbi.nlm.nih.gov/pubmed/24581042
http://dx.doi.org/10.1186/1754-1611-8-7

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