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Regulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NF-κB/IκB pathway

BACKGROUND: Cyclooxygenase-2 (COX-2) has been shown to be highly expressed in a broad series of primary endometrial tumors and its expression may be closely associated with parameters of tumor aggressiveness. In human endometrial cancer, tumor suppressor phosphatase tensin homologue (PTEN) is freque...

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Detalles Bibliográficos
Autores principales: St-Germain, Marie-Eve, Gagnon, Veronique, Parent, Sophie, Asselin, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC394342/
https://www.ncbi.nlm.nih.gov/pubmed/15016316
http://dx.doi.org/10.1186/1476-4598-3-7