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The Flögel-three-component reaction with dicarboxylic acids – an approach to bis(β-alkoxy-β-ketoenamides) for the synthesis of complex pyridine and pyrimidine derivatives

An extension of the substrate scope of the Flögel-three-component reaction of lithiated alkoxyallenes, nitriles and carboxylic acids is presented. The use of dicarboxylic acids allowed the preparation of symmetrical bis(β-ketoenamides) from simple starting materials in moderate yields. Cyclocondensa...

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Detalles Bibliográficos
Autores principales: Bera, Mrinal K, Domínguez, Moisés, Hommes, Paul, Reissig, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943434/
https://www.ncbi.nlm.nih.gov/pubmed/24605160
http://dx.doi.org/10.3762/bjoc.10.37