Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

BACKGROUND: The Illumina HumanMethylation450 BeadChip (HM450K) measures the DNA methylation of 485,512 CpGs in the human genome. The technology relies on hybridization of genomic fragments to probes on the chip. However, certain genomic factors may compromise the ability to measure methylation using...

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Detalles Bibliográficos
Autores principales: Naeem, Haroon, Wong, Nicholas C, Chatterton, Zac, Hong, Matthew K H, Pedersen, John S, Corcoran, Niall M, Hovens, Christopher M, Macintyre, Geoff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943510/
https://www.ncbi.nlm.nih.gov/pubmed/24447442
http://dx.doi.org/10.1186/1471-2164-15-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943510/
https://www.ncbi.nlm.nih.gov/pubmed/24447442
http://dx.doi.org/10.1186/1471-2164-15-51

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