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Caffeine induces alveolar apoptosis in the hyperoxia-exposed developing mouse lung

BACKGROUND: Caffeine is a nonspecific adenosine receptor antagonist used in premature neonates to treat apnea of prematurity. While its use may reduce the incidence of bronchopulmonary dysplasia (BPD), the precise mechanisms remain unknown. Evidence of increased adenosine levels are noted in chronic...

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Detalles Bibliográficos
Autores principales: Dayanim, Sara, Lopez, Benjamin, Maisonet, Tiffany M., Grewal, Sungat, Londhe, Vedang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943688/
https://www.ncbi.nlm.nih.gov/pubmed/24321990
http://dx.doi.org/10.1038/pr.2013.233