Fusion of Antigen to a Dendritic Cell Targeting Chemokine Combined with Adjuvant Yields a Malaria DNA Vaccine with Enhanced Protective Capabilities

Although sterilizing immunity to malaria can be elicited by irradiated sporozoite vaccination, no clinically practical subunit vaccine has been shown to be capable of preventing the approximately 600,000 annual deaths attributed to this infection. DNA vaccines offer several potential advantages for...

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Detalles Bibliográficos
Autores principales: Luo, Kun, Zhang, Hong, Zavala, Fidel, Biragyn, Arya, Espinosa, Diego A., Markham, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943962/
https://www.ncbi.nlm.nih.gov/pubmed/24599116
http://dx.doi.org/10.1371/journal.pone.0090413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943962/
https://www.ncbi.nlm.nih.gov/pubmed/24599116
http://dx.doi.org/10.1371/journal.pone.0090413

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