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Unlike Twins: An NMR Comparison of Two α-Synuclein Polymorphs Featuring Different Toxicity

We structurally compare, using solid-state NMR, two different polymorphs of α-synuclein which, as established recently, display contrasting biochemical properties, toxicity, and tropism for cells. We show that both forms, which can each be produced as a pure polymorph, are greatly different in secon...

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Detalles Bibliográficos
Autores principales: Gath, Julia, Bousset, Luc, Habenstein, Birgit, Melki, Ronald, Böckmann, Anja, Meier, Beat H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944079/
https://www.ncbi.nlm.nih.gov/pubmed/24599158
http://dx.doi.org/10.1371/journal.pone.0090659