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C57BL/6N Albino/Agouti Mutant Mice as Embryo Donors for Efficient Germline Transmission of C57BL/6 ES Cells

We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format th...

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Detalles Bibliográficos
Autores principales: Zevnik, Branko, Uyttersprot, Nathalie C., Perez, Ana V., Bothe, Gerald W. M., Kern, Heidrun, Kauselmann, Gunther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944090/
https://www.ncbi.nlm.nih.gov/pubmed/24599260
http://dx.doi.org/10.1371/journal.pone.0090570