Phosphodiesterase 3/4 Inhibitor Zardaverine Exhibits Potent and Selective Antitumor Activity against Hepatocellular Carcinoma Both In Vitro and In Vivo Independently of Phosphodiesterase Inhibition

Hepatocellular carcinoma (HCC) is the fifth common malignancy worldwide and the third leading cause of cancer-related death. Targeted therapies for HCC are being extensively developed with the limited success of sorafinib. In the present study, we investigated the potential antitumor activity of zar...

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Detalles Bibliográficos
Autores principales: Sun, Liping, Quan, Haitian, Xie, Chengying, Wang, Lei, Hu, Youhong, Lou, Liguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944092/
https://www.ncbi.nlm.nih.gov/pubmed/24598942
http://dx.doi.org/10.1371/journal.pone.0090627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944092/
https://www.ncbi.nlm.nih.gov/pubmed/24598942
http://dx.doi.org/10.1371/journal.pone.0090627

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