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Vitamin D endocrine system and osteoclasts

Vitamin D was discovered as an anti-rachitic agent preventing a failure in bone mineralization, but it is now established that the active form of vitamin D(3) (1α,25(OH)(2)D(3)) induces bone resorption. Discovery of the receptor activator of nuclear factor -κB ligand (RANKL) uncovered the molecular...

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Detalles Bibliográficos
Autores principales: Takahashi, Naoyuki, Udagawa, Naoyuki, Suda, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944126/
https://www.ncbi.nlm.nih.gov/pubmed/24605212
http://dx.doi.org/10.1038/bonekey.2013.229