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Vitamin D endocrine system and osteoclasts
Vitamin D was discovered as an anti-rachitic agent preventing a failure in bone mineralization, but it is now established that the active form of vitamin D(3) (1α,25(OH)(2)D(3)) induces bone resorption. Discovery of the receptor activator of nuclear factor -κB ligand (RANKL) uncovered the molecular...
Autores principales: | Takahashi, Naoyuki, Udagawa, Naoyuki, Suda, Tatsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944126/ https://www.ncbi.nlm.nih.gov/pubmed/24605212 http://dx.doi.org/10.1038/bonekey.2013.229 |
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