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Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer

The discovery of underlying mechanisms of drug resistance, and the development of novel agents to target these pathways, is a priority for patients with advanced colorectal cancer (CRC). We previously undertook a systems biology approach to design a functional genomic screen and identified fibroblas...

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Detalles Bibliográficos
Autores principales: Turkington, R C, Longley, D B, Allen, W L, Stevenson, L, McLaughlin, K, Dunne, P D, Blayney, J K, Salto-Tellez, M, Van Schaeybroeck, S, Johnston, P G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944229/
https://www.ncbi.nlm.nih.gov/pubmed/24503538
http://dx.doi.org/10.1038/cddis.2014.10