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Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer
Sirtuin-3 (SIRT3), a major mitochondria NAD+-dependent deacetylase, may target mitochondrial proteins for lysine deacetylation and also regulate cellular functions. And, SIRT3 is an emerging instrumental regulator of the mitochondrial adaptive response to stress, such as metabolic reprogramming and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944233/ https://www.ncbi.nlm.nih.gov/pubmed/24503539 http://dx.doi.org/10.1038/cddis.2014.14 |