Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer

Sirtuin-3 (SIRT3), a major mitochondria NAD+-dependent deacetylase, may target mitochondrial proteins for lysine deacetylation and also regulate cellular functions. And, SIRT3 is an emerging instrumental regulator of the mitochondrial adaptive response to stress, such as metabolic reprogramming and...

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Detalles Bibliográficos
Autores principales: Chen, Y, Fu, L L, Wen, X, Wang, X Y, Liu, J, Cheng, Y, Huang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944233/
https://www.ncbi.nlm.nih.gov/pubmed/24503539
http://dx.doi.org/10.1038/cddis.2014.14

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