S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis

The intrinsic pathway of apoptotic cell death is mainly mediated by the BCL-2-associated X (BAX) protein through permeabilization of the mitochondrial outer membrane (MOM) and the concomitant release of cytochrome c into the cytosol. In healthy, non-apoptotic cells, BAX is predominantly localized in...

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Detalles Bibliográficos
Autores principales: Fröhlich, M, Dejanovic, B, Kashkar, H, Schwarz, G, Nussberger, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944235/
https://www.ncbi.nlm.nih.gov/pubmed/24525733
http://dx.doi.org/10.1038/cddis.2014.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944235/
https://www.ncbi.nlm.nih.gov/pubmed/24525733
http://dx.doi.org/10.1038/cddis.2014.17

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