Necroptosis induced by RIPK3 requires MLKL but not Drp1

Necroptosis is a mechanism by which cells can kill themselves that does not require caspase activity or the presence of the pro-apoptotic Bcl-2 family members Bax or Bak. It has been reported that RIPK3 (receptor interacting protein kinase 3) activates MLKL (mixed lineage kinase domain-like) to caus...

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Detalles Bibliográficos
Autores principales: Moujalled, D M, Cook, W D, Murphy, J M, Vaux, D L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944236/
https://www.ncbi.nlm.nih.gov/pubmed/24577084
http://dx.doi.org/10.1038/cddis.2014.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944236/
https://www.ncbi.nlm.nih.gov/pubmed/24577084
http://dx.doi.org/10.1038/cddis.2014.18

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