Mahogunin-mediated α-tubulin ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation

Mahogunin ring finger-1 (MGRN1) is a cytosolic ubiquitin ligase whose disruption or interaction with some isoforms of cytosolically exposed prion protein leads to spongiform neurodegeneration and also lack of which results in reduced embryonic viability due to mispatterning of the left–right (LR) ax...

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Detalles Bibliográficos
Autores principales: Srivastava, D, Chakrabarti, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944237/
https://www.ncbi.nlm.nih.gov/pubmed/24556679
http://dx.doi.org/10.1038/cddis.2014.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944237/
https://www.ncbi.nlm.nih.gov/pubmed/24556679
http://dx.doi.org/10.1038/cddis.2014.1

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