The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1

The tumour suppressor PML (promyelocytic leukaemia protein) regulates several cellular pathways involving cell growth, apoptosis, differentiation and senescence. PML also has an important role in the regulation of stem cell proliferation and differentiation. Here, we show the involvement of the heli...

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Detalles Bibliográficos
Autores principales: Mathieu, M G, Miles, A K, Ahmad, M, Buczek, M E, Pockley, A G, Rees, R C, Regad, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944245/
https://www.ncbi.nlm.nih.gov/pubmed/24525737
http://dx.doi.org/10.1038/cddis.2014.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944245/
https://www.ncbi.nlm.nih.gov/pubmed/24525737
http://dx.doi.org/10.1038/cddis.2014.29

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