Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma

Cancer treatments induce cell stress to trigger apoptosis in tumor cells. Many cancers repress these apoptotic signals through alterations in the Bcl2 proteins that regulate this process. Therapeutics that target these specific survival biases are in development, and drugs that inhibit Bcl2 activiti...

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Detalles Bibliográficos
Autores principales: Laetsch, T W, Liu, X, Vu, A, Sliozberg, M, Vido, M, Elci, O U, Goldsmith, K C, Hogarty, M D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944256/
https://www.ncbi.nlm.nih.gov/pubmed/24556687
http://dx.doi.org/10.1038/cddis.2014.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944256/
https://www.ncbi.nlm.nih.gov/pubmed/24556687
http://dx.doi.org/10.1038/cddis.2014.40

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