Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

The antidiabetic drug metformin exerts chemopreventive and antineoplastic effects in many types of malignancies. However, the mechanisms responsible for metformin actions appear diverse and may differ in different types of cancer. Understanding the molecular and cellular mechanisms specific for diff...

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Detalles Bibliográficos
Autores principales: Feng, Y, Ke, C, Tang, Q, Dong, H, Zheng, X, Lin, W, Ke, J, Huang, J, Yeung, S-CJ, Zhang, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944271/
https://www.ncbi.nlm.nih.gov/pubmed/24577086
http://dx.doi.org/10.1038/cddis.2014.59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944271/
https://www.ncbi.nlm.nih.gov/pubmed/24577086
http://dx.doi.org/10.1038/cddis.2014.59

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