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Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice

Epidemiological studies have suggested an association between pesticide exposure and Parkinson's disease. In this study, we examined the neurotoxicity of an organochlorine pesticide, heptachlor, in vitro and in vivo. In cultured SH-SY5Y cells, heptachlor induced mitochondria-mediated apoptosis....

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Detalles Bibliográficos
Autores principales: Hong, Seokheon, Hwang, Joohyun, Kim, Joo Yeon, Shin, Ki Soon, Kang, Shin Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944446/
https://www.ncbi.nlm.nih.gov/pubmed/24577234
http://dx.doi.org/10.1038/emm.2014.12