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Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice
Epidemiological studies have suggested an association between pesticide exposure and Parkinson's disease. In this study, we examined the neurotoxicity of an organochlorine pesticide, heptachlor, in vitro and in vivo. In cultured SH-SY5Y cells, heptachlor induced mitochondria-mediated apoptosis....
Autores principales: | Hong, Seokheon, Hwang, Joohyun, Kim, Joo Yeon, Shin, Ki Soon, Kang, Shin Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944446/ https://www.ncbi.nlm.nih.gov/pubmed/24577234 http://dx.doi.org/10.1038/emm.2014.12 |
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