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Clinical implications of high NQO1 expression in breast cancers

BACKGROUND: NAD (P) H: quinone oxidoreductase 1 (NQO1) is a xenobiotic metabolizing enzyme that detoxifies chemical stressors and antioxidants, providing cytoprotection in normal tissues. However, high-level expression of NQO1 has been correlated with numerous human malignancies, suggesting a role i...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zhang, Yan, Wu, Qunying, Cui, Xuelian, Lin, Zhenhua, Liu, Shuangping, Chen, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944477/
https://www.ncbi.nlm.nih.gov/pubmed/24499631
http://dx.doi.org/10.1186/1756-9966-33-14