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Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models

Mouse colorectal cancer (CRC) models generated by orthotopic microinjection of human CRC cell lines reproduce the pattern of lymphatic, haematological and transcoelomic spread but generate low metastatic efficiency. Our aim was to develop a new strategy that could increase the metastatic efficiency...

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Detalles Bibliográficos
Autores principales: Alamo, Patricia, Gallardo, Alberto, Pavón, Miguel A., Casanova, Isolda, Trias, Manuel, Mangues, Maria A., Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon, Céspedes, Maria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944498/
https://www.ncbi.nlm.nih.gov/pubmed/24487410
http://dx.doi.org/10.1242/dmm.013995