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Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models
Mouse colorectal cancer (CRC) models generated by orthotopic microinjection of human CRC cell lines reproduce the pattern of lymphatic, haematological and transcoelomic spread but generate low metastatic efficiency. Our aim was to develop a new strategy that could increase the metastatic efficiency...
Autores principales: | Alamo, Patricia, Gallardo, Alberto, Pavón, Miguel A., Casanova, Isolda, Trias, Manuel, Mangues, Maria A., Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon, Céspedes, Maria V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944498/ https://www.ncbi.nlm.nih.gov/pubmed/24487410 http://dx.doi.org/10.1242/dmm.013995 |
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