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Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates

AIM: The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported. METHOD AND MATERIALS: About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol...

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Detalles Bibliográficos
Autores principales: Pyreddy, Suneela, Kumar, Pandurangan Dinesh, Kumar, Palanirajan Vijayaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944612/
https://www.ncbi.nlm.nih.gov/pubmed/24678457
http://dx.doi.org/10.4103/2230-973X.127735