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A novel strategy inducing autophagic cell death in Burkitt's lymphoma cells with anti-CD19-targeted liposomal rapamycin

Relapsed or refractory Burkitt's lymphoma often has a poor prognosis in spite of intensive chemotherapy that induces apoptotic and/or necrotic death of lymphoma cells. Rapamycin (Rap) brings about autophagy, and could be another treatment. Further, anti-CD19-targeted liposomal delivery may enab...

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Detalles Bibliográficos
Autores principales: Ono, K, Sato, T, Iyama, S, Tatekoshi, A, Hashimoto, A, Kamihara, Y, Horiguchi, H, Kikuchi, S, Kawano, Y, Takada, K, Hayashi, T, Miyanishi, K, Sato, Y, Takimoto, R, Kobune, M, Kato, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944660/
https://www.ncbi.nlm.nih.gov/pubmed/24510029
http://dx.doi.org/10.1038/bcj.2014.2