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The M1 and M2 paradigm of macrophage activation: time for reassessment

Macrophages are endowed with a variety of receptors for lineage-determining growth factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues, macrophages mature and are activated in a dynamic response to combinations of these stimuli to acquire specialized functiona...

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Detalles Bibliográficos
Autores principales: Martinez, Fernando O., Gordon, Siamon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944738/
https://www.ncbi.nlm.nih.gov/pubmed/24669294
http://dx.doi.org/10.12703/P6-13