Cargando…

Botulinum Toxin Suppression of CNS Network Activity In Vitro

The botulinum toxins are potent agents which disrupt synaptic transmission. While the standard method for BoNT detection and quantification is based on the mouse lethality assay, we have examined whether alterations in cultured neuronal network activity can be used to detect the functional effects o...

Descripción completa

Detalles Bibliográficos
Autores principales: Pancrazio, Joseph J., Gopal, Kamakshi, Keefer, Edward W., Gross, Guenter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944787/
https://www.ncbi.nlm.nih.gov/pubmed/24688538
http://dx.doi.org/10.1155/2014/732913